Understanding how the gut microbiome shapes maternal and neonatal immunity.

The Zeng Laboratory at Weill Cornell Medicine studies host-microbiome interactions during early life to uncover mechanisms that prevent inflammatory disease.

OUR RESEARCH

Maternal Immunity

We investigate how maternal immune adaption during pregnancy promotes tolerance and protects against inflammatory disease.

Gut Microbiome

We define how early-life microbial communities shape immune development and long-term health outcomes.

Translational Therapeutics

We develop microbiome and immune-based strategies to prevent and treat inflammatory diseases in mothers and infants.

LATEST UPDATES

RECENT PUBLICATIONS

Nat Immunol. 2025

Cell Host Microbe. 2025

J Exp Med. 2025

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LAB NEWS

Zeng Lab Annual Retreat 2025

Welcome New Lab Members

Zeng Lab in the News

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AWARDS

NIH MIRA Award

Burroughs Welcome Fund Career Award at the Scientific Interface

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OUR PEOPLE

Melody Y. Zeng, Ph.D.
Principal Investigator

Our work sits at the intersection of immunology, microbiology, and maternal-child health to translate fundamental discoveries into therapies that improve lives.

READ MORE ABOUT DR. ZENG

Join the Zeng Laboratory

We are always looking for motivated scientists to join our mission.